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IXICO webinar session;
Using MRI to assess safety, efficacy and eligibility of new Alzheimer's Disease therapies. This Webinar is now over. “We were overwhelmed with the turnout and level of participation”.Ciaran Cooper. VP Business Development.
A re-run of this session will be announced soon.
For more information  Click here

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Publications

IXICO's scientific expertise is demonstrated by the publication track record of its founders and employees.

Click the appropriate link to view our publications:

Computed Tomography

1: McClelland JR, Webb S, McQuaid D, Binnie DM, Hawkes DJ.

Tracking 'differential organ motion' with a 'breathing' multileaf collimator: magnitude of problem assessed using 4D CT data and a motion-compensation strategy.

Phys Med Biol. 2007 Aug 21;52(16):4805-26. Epub 2007 Jul 24.


2: Penney GP, Edwards PJ, Hipwell JH, Slomczykowski M, Revie I, Hawkes DJ.
Postoperative calculation of acetabular cup position using 2-D-3-D registration.
IEEE Trans Biomed Eng. 2007 Jul;54(7):1342-8.


3: McClelland JR, Blackall JM, Tarte S, Chandler AC, Hughes S, Ahmad S, Landau DB, Hawkes DJ.
A continuous 4D motion model from multiple respiratory cycles for use in lung radiotherapy.
Med Phys. 2006 Sep;33(9):3348-58.


4: Blackall JM, Ahmad S, Miquel ME, McClelland JR, Landau DB, Hawkes DJ.
MRI-based measurements of respiratory motion variability and assessment of imaging strategies for radiotherapy planning.
Phys Med Biol. 2006 Sep 7;51(17):4147-69. Epub 2006 Aug 8.


5: Penney GP, Barratt DC, Chan CS, Slomczykowski M, Carter TJ, Edwards PJ, Hawkes DJ.
Cadaver validation of intensity-based ultrasound to CT registration.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2005;8(Pt 2):1000-7.

6: Edwards PJ, Nijmeh AD, McGurk M, Odell E, Fenlon MR, Marsden PK, Hawkes DJ.
Validation of PET imaging by alignment to histology slices.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2005;8(Pt 2):968-75.

7: Barratt DC, Penney G, Chan CS, Slomczykowski M, Carter TJ, Edwards PJ, Hawkes
DJ.

Self-calibrating ultrasound-to-CT bone registration.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2005;8(Pt 1):605-12.

8: Barratt DC, Penney GP, Chan CS, Slomczykowski M, Carter TJ, Edwards PJ, Hawkes
DJ.
Self-calibrating 3D-ultrasound-based bone registration for minimally invasive
orthopedic surgery.
IEEE Trans Med Imaging. 2006 Mar;25(3):312-23.

9: Penney GP, Barratt DC, Chan CS, Slomczykowski M, Carter TJ, Edwards PJ, Hawkes
DJ.

Cadaver validation of intensity-based ultrasound to CT registration.
Med Image Anal. 2006 Jun;10(3):385-95. Epub 2006 Mar 7.

10: Blackall JM, Penney GP, King AP, Hawkes DJ.

Alignment of sparse freehand 3-D ultrasound with preoperative images of the liver
using models of respiratory motion and deformation.
IEEE Trans Med Imaging. 2005 Nov;24(11):1405-16.

11: Hu MT, Scherfler C, Khan NL, Hajnal JV, Lees AJ, Quinn N, Wood NW, Brooks DJ.
Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and
Parkin-linked Parkinson's disease.
Mov Disord. 2006 Mar;21(3):299-305.

12: Hipwell JH, Penney GP, McLaughlin RA, Rhode K, Summers P, Cox TC, Byrne JV,
Noble JA, Hawkes DJ.

Intensity-based 2-D-3-D registration of cerebral angiograms.
IEEE Trans Med Imaging. 2003 Nov;22(11):1417-26.

13: Rueckert D, Frangi AF, Schnabel JA.
Automatic construction of 3-D statistical deformation models of the brain using
nonrigid registration.
IEEE Trans Med Imaging. 2003 Aug;22(8):1014-25.

14: Penney GP, Little JA, Weese J, Hill DL, Hawkes DJ.
Deforming a preoperative volume to represent the intraoperative scene.
Comput Aided Surg. 2002;7(2):63-73.

15: Penney GP, Batchelor PG, Hill DL, Hawkes DJ, Weese J.
Validation of a two- to three-dimensional registration algorithm for aligning
preoperative CT images and intraoperative fluoroscopy images.
Med Phys. 2001 Jun;28(6):1024-32.

16: Weese J, Penney GP, Desmedt P, Buzug TM, Hill DL, Hawkes DJ.
Voxel-based 2-D/3-D registration of fluoroscopy images and CT scans for
image-guided surgery.
IEEE Trans Inf Technol Biomed. 1997 Dec;1(4):284-93.

17: Hill DL, Smith AD, Simmons A, Maurer CR Jr, Cox TC, Elwes R, Brammer M,
Hawkes DJ, Polkey CE.

Sources of error in comparing functional magnetic resonance imaging and invasive
electrophysiological recordings.
J Neurosurg. 2000 Aug;93(2):214-23.

18: Edwards PJ, Hill DL, Little JA, Hawkes DJ.
A three-component deformation model for image-guided surgery.
Med Image Anal. 1998 Dec;2(4):355-67.

19: Penney GP, Weese J, Little JA, Desmedt P, Hill DL, Hawkes DJ.
A comparison of similarity measures for use in 2-D-3-D medical image
registration.
IEEE Trans Med Imaging. 1998 Aug;17(4):586-95.

20: Thomas EL, Saeed N, Hajnal JV, Brynes A, Goldstone AP, Frost G, Bell JD.
Magnetic resonance imaging of total body fat.
J Appl Physiol. 1998 Nov;85(5):1778-85.

21: Hill DL, Maurer CR Jr, Studholme C, Fitzpatrick JM, Hawkes DJ.
Correcting scaling errors in tomographic images using a nine degree of freedom
registration algorithm.
J Comput Assist Tomogr. 1998 Mar-Apr;22(2):317-23.

22: West J, Fitzpatrick JM, Wang MY, Dawant BM, Maurer CR Jr, Kessler RM,
Maciunas RJ, Barillot C, Lemoine D, Collignon A, Maes F, Suetens P, Vandermeulen
D, van den Elsen PA, Napel S, Sumanaweera TS, Harkness B, Hemler PF, Hill DL,
Hawkes DJ, Studholme C, Maintz JB, Viergever MA, Malandain G, Woods RP, et al.

Comparison and evaluation of retrospective intermodality brain image registration
techniques.
J Comput Assist Tomogr. 1997 Jul-Aug;21(4):554-66.

23: Wong JC, Studholme C, Hawkes DJ, Maisey MN.
Evaluation of the limits of visual detection of image misregistration in a brain
fluorine-18 fluorodeoxyglucose PET-MRI study.
Eur J Nucl Med. 1997 Jun;24(6):642-50.

24: Hill DL, Langsaeter LA, Poynter-Smith PN, Emery CL, Summers PE, Keevil SF,
Pracy JP, Walsh R, Hawkes DJ, Gleeson MJ.

Feasibility study of magnetic resonance imaging-guided intranasal flexible
microendoscopy.
Comput Aided Surg. 1997;2(5):264-75.

25: Studholme C, Hill DL, Hawkes DJ.
Automated three-dimensional registration of magnetic resonance and positron
emission tomography brain images by multiresolution optimization of voxel
similarity measures.
Med Phys. 1997 Jan;24(1):25-35.

26: Wong WL, Hussain K, Chevretton E, Hawkes DJ, Baddeley H, Maisey M, McGurk M.
Validation and clinical application of computer-combined computed tomography and
positron emission tomography with 2-[18F]fluoro-2-deoxy-D-glucose head and neck
images.
Am J Surg. 1996 Dec;172(6):628-32.

27: Studholme C, Hill DL, Hawkes DJ.
Automated 3-D registration of MR and CT images of the head.
Med Image Anal. 1996 Jun;1(2):163-75.

28: Gandhe AJ, Hill DL, Studholme C, Hawkes DJ, Ruff CF, Cox TC, Gleeson MJ, Strong AJ.
Combined and three-dimensional rendered multimodal data for planning cranial base
surgery: a prospective evaluation.
Neurosurgery. 1994 Sep;35(3):463-70; discussion 471.

29: Hill DL, Hawkes DJ, Gleeson MJ, Cox TC, Strong AJ, Wong WL, Ruff CF, Kitchen ND, Thomas DG, Sofat A, et al.
Accurate frameless registration of MR and CT images of the head: applications in
planning surgery and radiation therapy.
Radiology. 1994 May;191(2):447-54.

30: Hill DL, Hawkes DJ, Hussain Z, Green SE, Ruff CF, Robinson GP.
Accurate combination of CT and MR data of the head: validation and applications
in surgical and therapy planning.
Comput Med Imaging Graph. 1993 Jul-Oct;17(4-5):357-63.

31: Hill DL, Hawkes DJ, Crossman JE, Gleeson MJ, Cox TC, Bracey EE, Strong AJ, Graves P.
Registration of MR and CT images for skull base surgery using point-like
anatomical features.
Br J Radiol. 1991 Nov;64(767):1030-5.

32: Hawkes DJ, Jackson DF, Parker RP.
Tissue analysis by dual-energy computed tomography.
Br J Radiol. 1986 Jun;59(702):537-42.

33: Jackson DF, Hawkes DJ.
Energy dependence in the spectral factor approach to computed tomography.
Phys Med Biol. 1983 Mar;28(3):289-93. No abstract available.

34: Husband JE, Hawkes DJ, Peckham MJ.
CT estimations of mean attenuation values and volume in testicular tumors: a comparison with surgical and histologic findings.
Radiology. 1982 Aug;144(3):553-8.

Magnetic Resonance Imaging

1. Maheswaran S, Barjat H, Rueckert D, Bate ST, Howlett DR, Tilling L, Smart SC, Pohlmann A, Richardson JC, Hartkens T, Hill DL, Upton N, Hajnal JV, James MF.
Brain Res .Longitudinal regional brain volume changes quantified in normal aging and Alzheimer's APP x PS1 mice using MRI.  2009 May 13 ;1270:19-32.

2. Clarkson MJ, Ourselin S, Nielsen C, Leung KK, Barnes J, Whitwell JL, Gunter JL, Hill DL, Weiner MW, Jack CR Jr, Fox NC; Alzheimer's Disease Neuroimaging Initiative. Neuroimage .
Comparison of phantom and registration scaling corrections using the ADNI cohort 2009 Oct 1 ;47(4):1506-13

3. Maheswaran S, Barjat H, Bate ST, Aljabar P, Hill DL, Tilling L, Upton N, James MF, Hajnal JV, Rueckert D. Neuroimage .
Analysis of serial magnetic resonance images of mouse brains using image registration. 2009 Feb 1 ;44(3): 692-700

4: Li Y, Hand JW, Wills T, Hajnal JV.
Numerically-simulated induced electric field and current density within a human model located close to a z-gradient coil.
J Magn Reson Imaging. 2007 Nov;26(5):1286-95.

5: Murgasova M, Dyet L, Edwards D, Rutherford M, Hajnal J, Rueckert D.
Segmentation of brain MRI in young children.
Acad Radiol. 2007 Nov;14(11):1350-66.

6: Aljabar P, Bhatia KK, Murgasova M, Hajnal JV, Boardman JP, Srinivasan L, Rutherford MA, Dyet LE, Edwards AD, Rueckert D.
Assessment of brain growth in early childhood using deformation-based morphometry.
Neuroimage. 2008 Jan 1;39(1):348-58. Epub 2007 Aug 24.

7: Hipwell JH, Tanner C, Crum WR, Schnabel JA, Hawkes DJ.
A new validation method for X-ray mammogram registration algorithms using a
projection model of breast X-ray compression.
IEEE Trans Med Imaging. 2007 Sep;26(9):1190-200.

8: Xue H, Srinivasan L, Jiang S, Rutherford M, Edwards AD, Rueckert D, Hajnal JV.
Automatic segmentation and reconstruction of the cortex from neonatal MRI.
Neuroimage. 2007 Nov 15;38(3):461-77. Epub 2007 Aug 7.

9: Rao A, Aljabar P, Rueckert D.
Hierarchical statistical shape analysis and prediction of sub-cortical brain structures.
Med Image Anal. 2007 Jun 28; [Epub ahead of print]

7: McClelland JR, Webb S, McQuaid D, Binnie DM, Hawkes DJ.
Tracking 'differential organ motion' with a 'breathing' multileaf collimator:
magnitude of problem assessed using 4D CT data and a motion-compensation strategy.
Phys Med Biol. 2007 Aug 21;52(16):4805-26. Epub 2007 Jul 24.

9: Jiang S, Xue H, Glover A, Rutherford M, Rueckert D, Hajnal JV.
MRI of moving subjects using multislice snapshot images with volume reconstruction (SVR): application to fetal, neonatal, and adult brain studies.
IEEE Trans Med Imaging. 2007 Jul;26(7):967-80.

10: Schmitz SA, O'Regan DP, Fitzpatrick J, Neuwirth C, Potter E, Tosi I, Hajnal
JV, Naoumova RP.

MRI at 3 Tesla detects no evidence for ischemic brain damage in intensively treated patients with homozygous familial hypercholesterolemia.
Neuroradiology. 2007 Nov;49(11):927-31. Epub 2007 Jul 21.

11: Xue H, Srinivasan L, Jiang S, Rutherford M, Edwards AD, Rueckert D, Hajnal JV.
Automatic cortical segmentation in the developing brain.
Inf Process Med Imaging. 2007;20:257-69.

12: Eckersley RJ, Tang MX, Chetty K, Hajnal JV.
Microbubble contrast agent detection using binary coded pulses.
Ultrasound Med Biol. 2007 Nov;33(11):1787-95. Epub 2007 Jul 16.

13: Foran AM, Fitzpatrick JA, Allsop J, Schmitz S, Franklin J, Pamboucas C, O'Regan D, Hajnal JV, Edwards AD.
Three-tesla cardiac magnetic resonance imaging for preterm infants.
Pediatrics. 2007 Jul;120(1):78-83.

14: Tanner C, Schnabel JA, Hill DL, Hawkes DJ, Degenhard A, Leach MO, Hose DR, Hall-Craggs MA, Usiskin SI.
Quantitative evaluation of free-form deformation registration for dynamic contrast-enhanced MR mammography.
Med Phys. 2007 Apr;34(4):1221-33.

15: Orton MR, Collins DJ, Walker-Samuel S, d'Arcy JA, Hawkes DJ, Atkinson D, Leach MO.
Bayesian estimation of pharmacokinetic parameters for DCE-MRI with a robust treatment of enhancement onset time.
Phys Med Biol. 2007 May 7;52(9):2393-408. Epub 2007 Apr 10.

16: Hammers A, Heckemann R, Koepp MJ, Duncan JS, Hajnal JV, Rueckert D, Aljabar P.
Automatic detection and quantification of hippocampal atrophy on MRI in temporal lobe epilepsy: a proof-of-principle study.
Neuroimage. 2007 May 15;36(1):38-47. Epub 2007 Mar 24.

17: Murgasova M, Dyet L, Edwards D, Rutherford M, Hajnal JV, Rueckert D.
Segmentation of brain MRI in young children.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2006;9(Pt 1):687-94.

18: Heckemann RA, Hajnal JV, Aljabar P, Rueckert D, Hammers A.
Multiclassifier fusion in human brain MR segmentation: modelling convergence.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2006;9(Pt 2):815-22.

19: Rueckert D, Aljabar P, Heckemann RA, Hajnal JV, Hammers A.
Diffeomorphic registration using B-splines.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2006;9(Pt 2):702-9.

20: Anjari M, Srinivasan L, Allsop JM, Hajnal JV, Rutherford MA, Edwards AD, Counsell SJ.
Diffusion tensor imaging with tract-based spatial statistics reveals local white matter abnormalities in preterm infants.
Neuroimage. 2007 Apr 15;35(3):1021-7. Epub 2007 Feb 8.

21: Counsell SJ, Dyet LE, Larkman DJ, Nunes RG, Boardman JP, Allsop JM, Fitzpatrick J, Srinivasan L, Cowan FM, Hajnal JV, Rutherford MA, Edwards AD.
Thalamo-cortical connectivity in children born preterm mapped using probabilistic magnetic resonance tractography.
Neuroimage. 2007 Feb 1;34(3):896-904. Epub 2006 Dec 15.

22: Reynolds PR, Larkman DJ, Haskard DO, Hajnal JV, Kennea NL, George AJ, Edwards AD.
Detection of vascular expression of E-selectin in vivo with MR imaging.
Radiology. 2006 Nov;241(2):469-76. Epub 2006 Sep 27.

23: Atkinson D, Counsell S, Hajnal JV, Batchelor PG, Hill DL, Larkman DJ.
Nonlinear phase correction of navigated multi-coil diffusion images.
Magn Reson Med. 2006 Nov;56(5):1135-9.

24: Blackall JM, Ahmad S, Miquel ME, McClelland JR, Landau DB, Hawkes DJ.MRI-based measurements of respiratory motion variability and assessment of imaging strategies for radiotherapy planning.
Phys Med Biol. 2006 Sep 7;51(17):4147-69. Epub 2006 Aug 8.

25: Malik SJ, Schmitz S, O'Regan D, Larkman DJ, Hajnal JV.
x-f Choice: reconstruction of undersampled dynamic MRI by data-driven alias
rejection applied to contrast-enhanced angiography.
Magn Reson Med. 2006 Oct;56(4):811-23. Erratum in: Magn Reson Med. 2007
Apr;57(4):813.

26: Dyet LE, Kennea N, Counsell SJ, Maalouf EF, Ajayi-Obe M, Duggan PJ, Harrison M, Allsop JM, Hajnal J, Herlihy AH, Edwards B, Laroche S, Cowan FM, Rutherford MA, Edwards AD.
Natural history of brain lesions in extremely preterm infants studied with serial
magnetic resonance imaging from birth and neurodevelopmental assessment.
Pediatrics. 2006 Aug;118(2):536-48.

27: Tanner C, Schnabel JA, Hill DL, Hawkes DJ, Leach MO, Hose DR.
Factors influencing the accuracy of biomechanical breast models.
Med Phys. 2006 Jun;33(6):1758-69.

28: Kapellou O, Counsell SJ, Kennea N, Dyet L, Saeed N, Stark J, Maalouf E, Duggan P, Ajayi-Obe M, Hajnal J, Allsop JM, Boardman J, Rutherford MA, Cowan F, Edwards AD.
Abnormal cortical development after premature birth shown by altered allometric scaling of brain growth.
PLoS Med. 2006 Aug;3(8):e265.

29: Malamateniou C, Counsell SJ, Allsop JM, Fitzpatrick JA, Srinivasan L, Cowan FM, Hajnal JV, Rutherford MA.
The effect of preterm birth on neonatal cerebral vasculature studied with magnetic resonance angiography at 3 Tesla.
Neuroimage. 2006 Sep;32(3):1050-9. Epub 2006 Jul 24.

30: Heckemann RA, Hajnal JV, Aljabar P, Rueckert D, Hammers A.
Automatic anatomical brain MRI segmentation combining label propagation and decision fusion.
Neuroimage. 2006 Oct 15;33(1):115-26. Epub 2006 Jul 24.

31: Sermesant M, Coudière Y, Moreau-Villèger V, Rhode KS, Hill DL, Razavi RS.
A fast-marching approach to cardiac electrophysiology simulation for XMR interventional imaging.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2005;8(Pt 2):607-15.

32: Sanchez-Ortiz GI, Sermesant M, Rhode KS, Chandrashekara R, Razavi R, Hill DL, Rueckert D.
Localization of abnormal conduction pathways for tachyarrhythmia treatment using tagged MRI.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2005;8(Pt 1):425-33.

33: Boardman JP, Counsell SJ, Rueckert D, Kapellou O, Bhatia KK, Aljabar P, Hajnal J, Allsop JM, Rutherford MA, Edwards AD.
Abnormal deep grey matter development following preterm birth detected using deformation-based morphometry.
Neuroimage. 2006 Aug 1;32(1):70-8. Epub 2006 May 3.

34: Batchelor PG, Calamante F, Tournier JD, Atkinson D, Hill DL, Connelly A.
Quantification of the shape of fiber tracts.
Magn Reson Med. 2006 Apr;55(4):894-903.

35: Hand JW, Li Y, Thomas EL, Rutherford MA, Hajnal JV.
Prediction of specific absorption rate in mother and fetus associated with MRI examinations during pregnancy.
Magn Reson Med. 2006 Apr;55(4):883-93.

36: Hamilton G, Allsop JM, Patel N, Forton DM, Thomas HC, O'Sullivan CP, Hajnal JV, Taylor-Robinson SD.
Variations due to analysis technique in intracellular pH measurements in simulated and in vivo 31P MR spectra of the human brain.
J Magn Reson Imaging. 2006 Apr;23(4):459-64.

37: Schmitz SA, O'Regan DP, Gibson D, Cunningham C, Fitzpatrick J, Allsop J, Larkman DJ, Hajnal JV.
Technical report: Magnetic resonance direct thrombus imaging at 3 T field strength in patients with lower limb deep vein thrombosis: a feasibility study.
Clin Radiol. 2006 Mar;61(3):282-6.

38: Larkman DJ, Batchelor PG, Atkinson D, Rueckert D, Hajnal JV.
Beyond the g-factor limit in sensitivity encoding using joint histogram entropy.
Magn Reson Med. 2006 Jan;55(1):153-60.

39: Blackall JM, Penney GP, King AP, Hawkes DJ.
Alignment of sparse freehand 3-D ultrasound with preoperative images of the liver using models of respiratory motion and deformation.
IEEE Trans Med Imaging. 2005 Nov;24(11):1405-16.

40: Callaghan MF, Larkman DJ, Hajnal JV.
Padé methods for reconstruction and feature extraction in magnetic resonance imaging.
Magn Reson Med. 2005 Dec;54(6):1490-502.

41: Crum WR, Tanner C, Hawkes DJ.
Anisotropic multi-scale fluid registration: evaluation in magnetic resonance breast imaging.
Phys Med Biol. 2005 Nov 7;50(21):5153-74. Epub 2005 Oct 19.

42: Hu MT, Scherfler C, Khan NL, Hajnal JV, Lees AJ, Quinn N, Wood NW, Brooks DJ.
Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and Parkin-linked Parkinson's disease.
Mov Disord. 2006 Mar;21(3):299-305.

43: O'Regan DP, Fitzgerald J, Allsop J, Gibson D, Larkman DJ, Cokkinos D, Hajnal JV, Schmitz SA.
A comparison of MR cholangiopancreatography at 1.5 and 3.0 Tesla.
Br J Radiol. 2005 Oct;78(934):894-8.

44: Batchelor PG, Atkinson D, Irarrazaval P, Hill DL, Hajnal J, Larkman D.
Matrix description of general motion correction applied to multishot images.
Magn Reson Med. 2005 Nov;54(5):1273-80.

45: Perperidis D, Mohiaddin RH, Rueckert D.
Spatio-temporal free-form registration of cardiac MR image sequences.
Med Image Anal. 2005 Oct;9(5):441-56.

46: Sermesant M, Rhode K, Sanchez-Ortiz GI, Camara O, Andriantsimiavona R, Hegde S, Rueckert D, Lambiase P, Bucknall C, Rosenthal E, Delingette H, Hill DL, Ayache N, Razavi R.
Simulation of cardiac pathologies using an electromechanical biventricular model
and XMR interventional imaging.
Med Image Anal. 2005 Oct;9(5):467-80.

47: Puri BK, Saeed N, Richardson AJ, Oatridge A, Hajnal JV, Bydder GM.
Schizophrenia syndromes associated with changes in ventricle-to-brain ratios: a serial high-resolution three-dimensional magnetic resonance imaging study in first-episode schizophrenia patients using subvoxel registration and semiautomated quantification.
Int J Clin Pract. 2005 Apr;59(4):399-402.

48: Shen Y, Larkman DJ, Counsell S, Pu IM, Edwards D, Hajnal JV.
Correction of high-order eddy current induced geometric distortion in diffusion-weighted echo-planar images.
Magn Reson Med. 2004 Nov;52(5):1184-9.

49: Chandrashekara R, Mohiaddin RH, Rueckert D.
Analysis of 3-D myocardial motion in tagged MR images using nonrigid image registration.
IEEE Trans Med Imaging. 2004 Oct;23(10):1245-50.

50: Adams EW, Harrison MC, Counsell SJ, Allsop JM, Kennea NL, Hajnal JV, Thornton AS, Duggan P, Edwards AD.
Increased lung water and tissue damage in bronchopulmonary dysplasia.
J Pediatr. 2004 Oct;145(4):503-7.

51: Rutherford M, Counsell S, Allsop J, Boardman J, Kapellou O, Larkman D, Hajnal J, Edwards D, Cowan F.
Diffusion-weighted magnetic resonance imaging in term perinatal brain injury: a comparison with site of lesion and time from birth.
Pediatrics. 2004 Oct;114(4):1004-14.

52: Lorenzo-Valdés M, Sanchez-Ortiz GI, Elkington AG, Mohiaddin RH, Rueckert D.
Segmentation of 4D cardiac MR images using a probabilistic atlas and the EM algorithm.
Med Image Anal. 2004 Sep;8(3):255-65.

53: Atkinson D, Larkman DJ, Batchelor PG, Hill DL, Hajnal JV.
Coil-based artifact reduction.
Magn Reson Med. 2004 Oct;52(4):825-30.

54: Crum WR, Hill DL, Hawkes DJ.
Information theoretic similarity measures in non-rigid registration.
Inf Process Med Imaging. 2003 Jul;18:378-87.

54: Holdcroft A, Oatridge A, Fusi L, Hajnal JV, Saeed N, Bydder GM.
Magnetic resonance imaging in preeclampsia and eclampsia complicated by visual
disturbance and other neurological abnormalities.
Int J Obstet Anesth. 2002 Oct;11(4):255-9.

55: Forton DM, Patel N, Prince M, Oatridge A, Hamilton G, Goldblatt J, Allsop JM, Hajnal JV, Thomas HC, Bassendine M, Jones DE, Taylor-Robinson SD.
Fatigue and primary biliary cirrhosis: association of globus pallidus magnetisation transfer ratio measurements with fatigue severity and blood manganese levels.
Gut. 2004 Apr;53(4):587-92.

56: Noble NM, Hill DL, Breeuwer M, Schnabel JA, Hawkes DJ, Gerritsen FA, Razavi R.
Myocardial delineation via registration in a polar coordinate system.
Acad Radiol. 2003 Dec;10(12):1349-58.

57: Razavi RS, Hill DL, Muthurangu V, Miquel ME, Taylor AM, Kozerke S, Baker EJ.
Three-dimensional magnetic resonance imaging of congenital cardiac anomalies.
Cardiol Young. 2003 Oct;13(5):461-5.

58: Razavi R, Hill DL, Keevil SF, Miquel ME, Muthurangu V, Hegde S, Rhode K, Barnett M, van Vaals J, Hawkes DJ, Baker E.
Cardiac catheterisation guided by MRI in children and adults with congenital
heart disease.
Lancet. 2003 Dec 6;362(9399):1877-82.

59: Penney GP, Blackall JM, Hamady MS, Sabharwal T, Adam A, Hawkes DJ.
Registration of freehand 3D ultrasound and magnetic resonance liver images.
Med Image Anal. 2004 Mar;8(1):81-91.

60: Hipwell JH, Penney GP, McLaughlin RA, Rhode K, Summers P, Cox TC, Byrne JV, Noble JA, Hawkes DJ.
Intensity-based 2-D-3-D registration of cerebral angiograms.
IEEE Trans Med Imaging. 2003 Nov;22(11):1417-26.

61: Counsell SJ, Kennea NL, Herlihy AH, Allsop JM, Harrison MC, Cowan FM, Hajnal JV, Edwards B, Edwards AD, Rutherford MA.
T2 relaxation values in the developing preterm brain.
AJNR Am J Neuroradiol. 2003 Sep;24(8):1654-60.

62: Rueckert D, Frangi AF, Schnabel JA.
Automatic construction of 3-D statistical deformation models of the brain using nonrigid registration.
IEEE Trans Med Imaging. 2003 Aug;22(8):1014-25.

63: Hamilton G, Patel N, Forton DM, Hajnal JV, Taylor-Robinson SD.
Prior knowledge for time domain quantification of in vivo brain or liver 31P MR spectra.
NMR Biomed. 2003 May;16(3):168-76.

64: Counsell SJ, Allsop JM, Harrison MC, Larkman DJ, Kennea NL, Kapellou O, Cowan FM, Hajnal JV, Edwards AD, Rutherford MA.
Diffusion-weighted imaging of the brain in preterm infants with focal and diffuse white matter abnormality.
Pediatrics. 2003 Jul;112(1 Pt 1):1-7.

65: Schnabel JA, Tanner C, Castellano-Smith AD, Degenhard A, Leach MO, Hose DR,
Hill DL, Hawkes DJ.

Validation of nonrigid image registration using finite-element methods: application to breast MR images.
IEEE Trans Med Imaging. 2003 Feb;22(2):238-47.

66: Hartkens T, Hill DL, Castellano-Smith AD, Hawkes DJ, Maurer CR Jr, Martin AJ, Hall WA, Liu H, Truwit CL.
Measurement and analysis of brain deformation during neurosurgery.
IEEE Trans Med Imaging. 2003 Jan;22(1):82-92.

67: Lim AK, Patel N, Hamilton G, Hajnal JV, Goldin RD, Taylor-Robinson SD.
The relationship of in vivo 31P MR spectroscopy to histology in chronic hepatitis C.
Hepatology. 2003 Apr;37(4):788-94.

68: Bydder M, Atkinson D, Larkman DJ, Hill DL, Hajnal JV.
SMASH navigators.
Magn Reson Med. 2003 Mar;49(3):493-500.

69: McLeish K, Hill DL, Atkinson D, Blackall JM, Razavi R.
A study of the motion and deformation of the heart due to respiration.
IEEE Trans Med Imaging. 2002 Sep;21(9):1142-50.

70: Oatridge A, Hajnal JV, Saeed N, Newlands ES, Curati WL, White SJ, Puri BK, Bydder GM.
Subvoxel image registration of multislice (2D) magnetic resonance images in patients with high-grade gliomas of the brain.
Clin Radiol. 2002 Dec;57(12):1098-108.

71: Batchelor PG, Castellano Smith AD, Hill DL, Hawkes DJ, Cox TC, Dean AF.
Measures of folding applied to the development of the human fetal brain.
IEEE Trans Med Imaging. 2002 Aug;21(8):953-65.

72: Degenhard A, Tanner C, Hayes C, Hawkes DJ, Leach MO; UK MRI Breast Screening Study.
Comparison between radiological and artificial neural network diagnosis in clinical screening.
Physiol Meas. 2002 Nov;23(4):727-39.

73: Oatridge A, Barnard ML, Puri BK, Taylor-Robinson SD, Hajnal JV, Saeed N, Bydder GM.
Changes in brain size with treatment in patients with hyper- or hypothyroidism.
AJNR Am J Neuroradiol. 2002 Oct;23(9):1539-44.

74: Puri BK, Counsell SJ, Zaman R, Main J, Collins AG, Hajnal JV, Davey NJ.
Relative increase in choline in the occipital cortex in chronic fatigue syndrome.
Acta Psychiatr Scand. 2002 Sep;106(3):224-6.

75: Adams EW, Counsell SJ, Hajnal JV, Cox PN, Kennea NL, Thornton AS, Bryan AC, Edwards AD.
Magnetic resonance imaging of lung water content and distribution in term and preterm infants.
Am J Respir Crit Care Med. 2002 Aug 1;166(3):397-402.

76: Bydder M, Larkman DJ, Hajnal JV.
Detection and elimination of motion artifacts by regeneration of k-space.
Magn Reson Med. 2002 Apr;47(4):677-86.

77: Puri BK, Bydder GM, Counsell SJ, Corridan BJ, Richardson AJ, Hajnal JV, Appel C, Mckee HM, Vaddadi KS, Horrobin DF.
MRI and neuropsychological improvement in Huntington disease following ethyl-EPA treatment.
Neuroreport. 2002 Jan 21;13(1):123-6.

78: Bydder M, Larkman DJ, Hajnal JV.
Combination of signals from array coils using image-based estimation of coil sensitivity profiles.
Magn Reson Med. 2002 Mar;47(3):539-48.

79: Oatridge A, Holdcroft A, Saeed N, Hajnal JV, Puri BK, Fusi L, Bydder GM.
Change in brain size during and after pregnancy: study in healthy women and women with preeclampsia.
AJNR Am J Neuroradiol. 2002 Jan;23(1):19-26.

80: Bydder M, Larkman DJ, Hajnal JV.
Generalized SMASH imaging.
Magn Reson Med. 2002 Jan;47(1):160-70.

81: Degenhard A, Tanner C, Hayes C, Hawkes DJ, Leach MO.
Pre-processed image reconstruction applied to breast and brain MR imaging.
Physiol Meas. 2001 Aug;22(3):589-604.

82: Larkman DJ, deSouza NM, Bydder M, Hajnal JV.
An investigation into the use of sensitivity-encoded techniques to increase
temporal resolution in dynamic contrast-enhanced breast imaging
J Magn Reson Imaging. 2001 Sep;14(3):329-35.

83: Herlihy AH, Oatridge A, Curati WL, Puri BK, Bydder GM, Hajnal JV.
FLAIR imaging using nonselective inversion pulses combined with slice excitation order cycling and k-space reordering to reduce flow artifacts.
Magn Reson Med. 2001 Aug;46(2):354-64.

84: Puri BK, Bydder GM, Chaudhuri KR, Al Saffar BY, Curati WL, White SJ, Mitchell L, Hajnal JV, Horrobin DF.
MRI changes in multiple sclerosis following treatment with lofepramine and L-phenylalanine.
Neuroreport. 2001 Jul 3;12(9):1821-4.

85: Curati WL, Oatridge A, Herlihy AH, Hajnal JV, Puri BK, Bydder GM.
Contributions of an adiabatic initial inversion pulse and K-space re-ordered by inversion-time at each slice position (KRISP) to control of CSF artifacts and visualization of the brain in FLAIR magnetic resonance imaging.
Clin Radiol. 2001 May;56(5):375-84.

86: Hu MT, White SJ, Herlihy AH, Chaudhuri KR, Hajnal JV, Brooks DJ.
A comparison of (18)F-dopa PET and inversion recovery MRI in the diagnosis of
Parkinson's disease.
Neurology. 2001 May 8;56(9):1195-200.

87: Herlihy AH, Hajnal JV, Curati WL, Virji N, Oatridge A, Puri BK, Bydder GM.
Reduction of CSF and blood flow artifacts on FLAIR images of the brain with k-space reordered by inversion time at each slice position (KRISP).
AJNR Am J Neuroradiol. 2001 May;22(5):896-904.

88: Puri BK, Hutton SB, Saeed N, Oatridge A, Hajnal JV, Duncan L, Chapman MJ, Barnes TR, Bydder GM, Joyce EM.
A serial longitudinal quantitative MRI study of cerebral changes in first-episode schizophrenia using image segmentation and subvoxel registration.
Psychiatry Res. 2001 Apr 10;106(2):141-50.

89: Oatridge A, Curati WL, Herlihy AH, Hajnal JV, Virji N, Puri BK, Bydder GM.
Evaluation of a FLAIR sequence designed to reduce CSF and blood flow artifacts by use of k-space reordered by inversion time at each slice position (KRISP) in high grade gliomas of the brain.
J Comput Assist Tomogr. 2001 Mar-Apr;25(2):251-6.

90: Larkman DJ, Hajnal JV, Herlihy AH, Coutts GA, Young IR, Ehnholm G.
Use of multicoil arrays for separation of signal from multiple slices simultaneously excited.
J Magn Reson Imaging. 2001 Feb;13(2):313-7.

91: Hajnal JV, Oatridge A, Herlihy AH, Bydder GM.
Reduction of CSF artifacts on FLAIR images by using adiabatic inversion pulses.
AJNR Am J Neuroradiol. 2001 Feb;22(2):317-22.

92: Larkman DJ, Herlihy AH, Coutts GA, Hajnal JV.
Elimination of magnetic field foldover artifacts in MR images.
J Magn Reson Imaging. 2000 Nov;12(5):795-7.

93: Thomas EL, Brynes AE, McCarthy J, Goldstone AP, Hajnal JV, Saeed N, Frost G, Bell JD.
Preferential loss of visceral fat following aerobic exercise, measured by magnetic resonance imaging.
Lipids. 2000 Jul;35(7):769-76.

94: Hand JW, Lagendijk JJ, Hajnal JV, Lau RW, Young IR.
SAR and temperature changes in the leg due to an RF decoupling coil at frequencies between 64 and 213 MHz.
J Magn Reson Imaging. 2000 Jul;12(1):68-74.

95: Hill DL, Smith AD, Simmons A, Maurer CR Jr, Cox TC, Elwes R, Brammer M, Hawkes DJ, Polkey CE.
Sources of error in comparing functional magnetic resonance imaging and invasive electrophysiological recordings.
J Neurosurg. 2000 Aug;93(2):214-23.

96: Adams EW, Counsell SJ, Hajnal JV, Allsop JM, Herlihy A, Edwards AD.
Investigation of lung disease in preterm infants using magnetic resonance imaging.
Biol Neonate. 2000 May;77 Suppl 1:17-20.

97: Holden M, Hill DL, Denton ER, Jarosz JM, Cox TC, Rohlfing T, Goodey J, Hawkes DJ.
Voxel similarity measures for 3-D serial MR brain image registration.
IEEE Trans Med Imaging. 2000 Feb;19(2):94-102.

98: Adams EW, Counsell SJ, Cox P, Al Nakhib L, Hajnal JV, Allsop J, Herlihy AH, Thornton A, Edwards AD.
Investigation of the role of lung liquid in the pathogenesis of lung disease in the preterm infant using magnetic resonance imaging
Early Hum Dev. 2000 Apr;58(1):76. No abstract available.

99: Puri BK, Richardson AJ, Horrobin DF, Easton T, Saeed N, Oatridge A, Hajnal JV, Bydder GM.
Eicosapentaenoic acid treatment in schizophrenia associated with symptom remission, normalisation of blood fatty acids, reduced neuronal membrane phospholipid turnover and structural brain changes.
Int J Clin Pract. 2000 Jan-Feb;54(1):57-63.

100: Sanchez-Ortiz GI, Rueckert D, Burger P.
Knowledge-based tensor anisotropic diffusion of cardiac magnetic resonance images.
Med Image Anal. 1999 Mar;3(1):77-101.

101: Young IR, Hajnal JV, Bydder GM.
The future of neurologic MR imaging.
AJNR Am J Neuroradiol. 2000 Jan;21(1):37-40. No abstract available.

102: Puri BK, Richardson AJ, Oatridge A, Hajnal JV, Saeed N.
Cerebral ventricular asymmetry in schizophrenia: a high resolution 3D magnetic resonance imaging study.
Int J Psychophysiol. 1999 Dec;34(3):207-11.

103: Rueckert D, Sonoda LI, Hayes C, Hill DL, Leach MO, Hawkes DJ.
Nonrigid registration using free-form deformations: application to breast MR images.
IEEE Trans Med Imaging. 1999 Aug;18(8):712-21.

104: Denton ER, Sonoda LI, Rueckert D, Rankin SC, Hayes C, Leach MO, Hill DL, Hawkes DJ.
Comparison and evaluation of rigid, affine, and nonrigid registration of breast MR images.
J Comput Assist Tomogr. 1999 Sep-Oct;23(5):800-5.

105: Edwards PJ, Hill DL, Little JA, Hawkes DJ.
A three-component deformation model for image-guided surgery.
Med Image Anal. 1998 Dec;2(4):355-67.

106: Atkinson D, Hill DL, Stoyle PN, Summers PE, Clare S, Bowtell R, Keevil SF.
Automatic compensation of motion artifacts in MRI.
Magn Reson Med. 1999 Jan;41(1):163-70.

107: Maurer CR Jr, Hill DL, Martin AJ, Liu H, McCue M, Rueckert D, Lloret D, Hall WA, Maxwell RE, Hawkes DJ, Truwit CL.
Investigation of intraoperative brain deformation using a 1.5-T interventional MR system: preliminary results.
IEEE Trans Med Imaging. 1998 Oct;17(5):817-25.

108: Saeed N, Puri BK, Oatridge A, Hajnal JV, Young IR.
Two methods for semi-automated quantification of changes in ventricular volume and their use in schizophrenia.
Magn Reson Imaging. 1998 Dec;16(10):1237-47.

109: Thomas EL, Saeed N, Hajnal JV, Brynes A, Goldstone AP, Frost G, Bell JD.
Magnetic resonance imaging of total body fat.
J Appl Physiol. 1998 Nov;85(5):1778-85.

110: Young IR, Bell JD, Hajnal JV, Jenkinson G, Ling J.
Evaluation of the stability of the proton chemical shifts of some metabolites other than water during thermal cycling of normal human muscle tissue.
J Magn Reson Imaging. 1998 Sep-Oct;8(5):1114-8.

111: Rico-Sanz J, Hajnal JV, Thomas EL, Mierisová S, Ala-Korpela M, Bell JD.
Intracellular and extracellular skeletal muscle triglyceride metabolism during alternating intensity exercise in humans.
J Physiol. 1998 Jul 15;510 ( Pt 2):615-22.

112: Atkinson D, Hill DL, Stoyle PN, Summers PE, Keevil SF.
Automatic correction of motion artifacts in magnetic resonance images using an entropy focus criterion.
IEEE Trans Med Imaging. 1997 Dec;16(6):903-10.

113: Hill DL, Maurer CR Jr, Studholme C, Fitzpatrick JM, Hawkes DJ.
Correcting scaling errors in tomographic images using a nine degree of freedom registration algorithm.
J Comput Assist Tomogr. 1998 Mar-Apr;22(2):317-23.

114: Bydder GM, Hajnal JV, Young IR.
MRI: use of the inversion recovery pulse sequence.
Clin Radiol. 1998 Mar;53(3):159-76. Review. No abstract available.

115: Summers PE, Bhalerao AH, Hawkes DJ.
Multiresolution, model-based segmentation of MR angiograms.
J Magn Reson Imaging. 1997 Nov-Dec;7(6):950-7.

116: Rueckert D, Burger P, Forbat SM, Mohiaddin RD, Yang GZ.
Automatic tracking of the aorta in cardiovascular MR images using deformable models.
IEEE Trans Med Imaging. 1997 Oct;16(5):581-90.

117: West J, Fitzpatrick JM, Wang MY, Dawant BM, Maurer CR Jr, Kessler RM,
Maciunas RJ, Barillot C, Lemoine D, Collignon A, Maes F, Suetens P, Vandermeulen
D, van den Elsen PA, Napel S, Sumanaweera TS, Harkness B, Hemler PF, Hill DL,
Hawkes DJ, Studholme C, Maintz JB, Viergever MA, Malandain G, Woods RP, et al.
Comparison and evaluation of retrospective intermodality brain image registration
techniques.
J Comput Assist Tomogr. 1997 Jul-Aug;21(4):554-66.

118: Wong JC, Studholme C, Hawkes DJ, Maisey MN.
Evaluation of the limits of visual detection of image misregistration in a brain fluorine-18 fluorodeoxyglucose PET-MRI study.
Eur J Nucl Med. 1997 Jun;24(6):642-50.

119: Rutherford MA, Pennock JM, Cowan FM, Saeed N, Hajnal JV, Bydder GM.
Detection of subtle changes in the brains of infants and children via subvoxel registration and subtraction of serial MR images.
AJNR Am J Neuroradiol. 1997 May;18(5):829-35.

120: Rutherford MA, Pennock JM, Cowan FM, Dubowitz LM, Hajnal JV, Bydder GM.
Does the brain regenerate after perinatal infarction?
Eur J Paediatr Neurol. 1997;1(1):13-7.

121: Hill DL, Langsaeter LA, Poynter-Smith PN, Emery CL, Summers PE, Keevil SF,
Pracy JP, Walsh R, Hawkes DJ, Gleeson MJ.
Feasibility study of magnetic resonance imaging-guided intranasal flexible microendoscopy.
Comput Aided Surg. 1997;2(5):264-75.

122: Studholme C, Hill DL, Hawkes DJ.
Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures.
Med Phys. 1997 Jan;24(1):25-35.

123: Wong WL, Hussain K, Chevretton E, Hawkes DJ, Baddeley H, Maisey M, McGurk M.
Validation and clinical application of computer-combined computed tomography and positron emission tomography with 2-[18F]fluoro-2-deoxy-D-glucose head and neck images.
Am J Surg. 1996 Dec;172(6):628-32.

124: Curati WL, Williams EJ, Oatridge A, Hajnal JV, Saeed N, Bydder GM.
Use of subvoxel registration and subtraction to improve demonstration of contrast enhancement in MRI of the brain.
Neuroradiology. 1996 Nov;38(8):717-23.

125: Hajnal JV, Roberts I, Wilson J, Oatridge A, Saeed N, Cox IJ, Ala-Korpela M, Bydder GM, Young IR.
Effect of profound ischaemia on human muscle: MRI, phosphorus MRS and near-infrared studies.
NMR Biomed. 1996 Oct;9(7):305-14.

126: Taylor-Robinson SD, Sargentoni J, Oatridge A, Bryant DJ, Hajnal JV, Marcus CD, Seery JP, Hodgson HJ, deSouza NM.
MR imaging and spectroscopy of the basal ganglia in chronic liver disease: correlation of T1-weighted contrast measurements with abnormalities in proton and phosphorus-31 MR spectra.
Metab Brain Dis. 1996 Sep;11(3):249-68.

127: Jäger HR, Williams EJ, Savage DG, Rule SA, Hajnal JV, Sikora K, Goldman JM, Bydder GM.
Assessment of brain changes with registered MR before and after bone marrow transplantation for chronic myeloid leukemia.
AJNR Am J Neuroradiol. 1996 Aug;17(7):1275-82.

128: Studholme C, Hill DL, Hawkes DJ.
Automated 3-D registration of MR and CT images of the head.
Med Image Anal. 1996 Jun;1(2):163-75.

129: Barnard ML, Schwieso JE, Thomas EL, Bell JD, Saeed N, Frost G, Bloom SR, Hajnal JV.
Development of a rapid and efficient magnetic resonance imaging technique for analysis of body fat distribution.
NMR Biomed. 1996 Jun;9(4):156-64.

130: Hajnal JV, Bydder GM, Young IR.
Stimulus-correlated signals in functional MR of the brain.
AJNR Am J Neuroradiol. 1996 Jun-Jul;17(6):1011-2. No abstract available.

131: Thomas DG, Doshi P, Colchester A, Hawkes DJ, Hill DL, Zhao J, Maitland N, Strong AJ, Evans RI.
Craniotomy guidance using a stereo-video-based tracking system.
Stereotact Funct Neurosurg. 1996;66(1-3):81-3.

132: Hajnal JV, Young IR, Bydder GM.
Studies strive to place fMRI on firm foundation.
Diagn Imaging (San Franc). 1995 Nov;17(11):112-7.

133: Hajnal JV, Saeed N, Oatridge A, Williams EJ, Young IR, Bydder GM.
Detection of subtle brain changes using subvoxel registration and subtraction of serial MR images.
J Comput Assist Tomogr. 1995 Sep-Oct;19(5):677-91.

134: Taylor-Robinson SD, Oatridge A, Hajnal JV, Burroughs AK, McIntyre N, deSouza NM.
MR imaging of the basal ganglia in chronic liver disease: correlation of T1-weighted and magnetisation transfer contrast measurements with liver dysfunction and neuropsychiatric status.
Metab Brain Dis. 1995 Jun;10(2):175-88.

135: Hajnal JV, Bydder GM, Young IR.
fMRI: does correlation imply activation?
NMR Biomed. 1995 May;8(3):97-100. No abstract available.

136: deSouza NM, Hajnal JV, Baudouin CJ.
Potential for increasing conspicuity of short-T1 lesions in the brain using magnetisation transfer imaging.
Neuroradiology. 1995 May;37(4):278-83

137: Hajnal JV, Saeed N, Soar EJ, Oatridge A, Young IR, Bydder GM.
A registration and interpolation procedure for subvoxel matching of serially acquired MR images.
J Comput Assist Tomogr. 1995 Mar-Apr;19(2):289-96.

138: Gandhe AJ, Hill DL, Studholme C, Hawkes DJ, Ruff CF, Cox TC, Gleeson MJ, Strong AJ.
Combined and three-dimensional rendered multimodal data for planning cranial base surgery: a prospective evaluation.
Neurosurgery. 1994 Sep;35(3):463-70; discussion 471.

139: Hill DL, Hawkes DJ, Gleeson MJ, Cox TC, Strong AJ, Wong WL, Ruff CF, Kitchen ND, Thomas DG, Sofat A, et al.
Accurate frameless registration of MR and CT images of the head: applications in planning surgery and radiation therapy.
Radiology. 1994 May;191(2):447-54.

140: Hajnal JV, Myers R, Oatridge A, Schwieso JE, Young IR, Bydder GM.
Artifacts due to stimulus correlated motion in functional imaging of the brain.
Magn Reson Med. 1994 Mar;31(3):283-91.

141: Hill DL, Hawkes DJ, Hussain Z, Green SE, Ruff CF, Robinson GP.
Accurate combination of CT and MR data of the head: validation and applications in surgical and therapy planning.
Comput Med Imaging Graph. 1993 Jul-Oct;17(4-5):357-63.

142: Neelin P, Crossman J, Hawkes DJ, Ma Y, Evans AC.
Validation of an MRI/PET landmark registration method using 3D simulated PET images and point simulations.
Comput Med Imaging Graph. 1993 Jul-Oct;17(4-5):351-6.

143: Oatridge A, Hajnal JV, Cowan FM, Baudouin CJ, Young IR, Bydder GM.
MRI diffusion-weighted imaging of the brain: contributions to image contrast from CSF signal reduction, use of a long echo time and diffusion effects.
Clin Radiol. 1993 Feb;47(2):82-90.

144: De Coene B, Hajnal JV, Pennock JM, Bydder GM.
MRI of the brain stem using fluid attenuated inversion recivery pulse sequences.
Neuroradiology. 1993;35(5):327-31.

145: White SJ, Hajnal JV, Young IR, Bydder GM.
Use of fluid-attenuated inversion-recovery pulse sequences for imaging the spinal cord.
Magn Reson Med. 1992 Nov;28(1):153-62.

146: De Coene B, Hajnal JV, Gatehouse P, Longmore DB, White SJ, Oatridge A, Pennock JM, Young IR, Bydder GM.
MR of the brain using fluid-attenuated inversion recovery (FLAIR) pulse sequences.
AJNR Am J Neuroradiol. 1992 Nov-Dec;13(6):1555-64.

147: Hill DL, Hawkes DJ, Crossman JE, Gleeson MJ, Cox TC, Bracey EE, Strong AJ, Graves P.
Registration of MR and CT images for skull base surgery using point-like anatomical features.
Br J Radiol. 1991 Nov;64(767):1030-5.

148: Lehmann ED, Hawkes DJ, Hill DL, Bird CF, Robinson GP, Colchester AC, Maisey MN.
Computer-aided interpretation of SPECT images of the brain using an MRI-derived 3D neuro-anatomical atlas.
Med Inform (Lond). 1991 Apr-Jun;16(2):151-66.

149: Rutherford MA, Cowan FM, Manzur AY, Dubowitz LM, Pennock JM, Hajnal JV, Young IR, Bydder GM.
MR imaging of anisotropically restricted diffusion in the brain of neonates and infants.
J Comput Assist Tomogr. 1991 Mar-Apr;15(2):188-98.

150: Doran M, Hajnal JV, Young IR, Bydder GM.
Diffusion-weighted MRI reveals white matter tracts.
Diagn Imaging (San Franc). 1991 Jan;13(1):50-5. No abstract available.

151: Doran M, Hajnal JV, Van Bruggen N, King MD, Young IR, Bydder GM.
Normal and abnormal white matter tracts shown by MR imaging using directional diffusion weighted sequences.
J Comput Assist Tomogr. 1990 Nov-Dec;14(6):865-73.

Positron Emission Tomography

1: Edwards PJ, Nijmeh AD, McGurk M, Odell E, Fenlon MR, Marsden PK, Hawkes DJ.
Validation of PET imaging by alignment to histology slices.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2005;8(Pt 2):968-75.

2: Hu MT, White SJ, Herlihy AH, Chaudhuri KR, Hajnal JV, Brooks DJ.
A comparison of (18)F-dopa PET and inversion recovery MRI in the diagnosis of Parkinson's disease.
Neurology. 2001 May 8;56(9):1195-200.

3: West J, Fitzpatrick JM, Wang MY, Dawant BM, Maurer CR Jr, Kessler RM, Maciunas RJ, Barillot C, Lemoine D, Collignon A, Maes F, Suetens P, Vandermeulen D, van den Elsen PA, Napel S, Sumanaweera TS, Harkness B, Hemler PF, Hill DL, Hawkes DJ, Studholme C, Maintz JB, Viergever MA, Malandain G, Woods RP, et al.
Comparison and evaluation of retrospective intermodality brain image registration techniques.
J Comput Assist Tomogr. 1997 Jul-Aug;21(4):554-66.

4: Wong JC, Studholme C, Hawkes DJ, Maisey MN.
Evaluation of the limits of visual detection of image misregistration in a brain fluorine-18 fluorodeoxyglucose PET-MRI study.
Eur J Nucl Med. 1997 Jun;24(6):642-50.

5: Studholme C, Hill DL, Hawkes DJ.
Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures.
Med Phys. 1997 Jan;24(1):25-35.

6: Wong WL, Hussain K, Chevretton E, Hawkes DJ, Baddeley H, Maisey M, McGurk M.
Validation and clinical application of computer-combined computed tomography and positron emission tomography with 2-[18F]fluoro-2-deoxy-D-glucose head and neck images.
Am J Surg. 1996 Dec;172(6):628-32.

7: Neelin P, Crossman J, Hawkes DJ, Ma Y, Evans AC.
Validation of an MRI/PET landmark registration method using 3D simulated PET images and point simulations.
Comput Med Imaging Graph. 1993 Jul-Oct;17(4-5):351-6.

Ultrasound

1: Eckersley RJ, Tang MX, Chetty K, Hajnal JV.
Microbubble contrast agent detection using binary coded pulses.
Ultrasound Med Biol. 2007 Nov;33(11):1787-95. Epub 2007 Jul 16.

2: Chetty K, Hajnal JV, Eckersley RJ.
Investigating the nonlinear microbubble response to chirp encoded, multipulse
sequences.
Ultrasound Med Biol. 2006 Dec;32(12):1887-95.

3: Penney GP, Barratt DC, Chan CS, Slomczykowski M, Carter TJ, Edwards PJ, Hawkes DJ.
Cadaver validation of intensity-based ultrasound to CT registration.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2005;8(Pt 2):1000-7.

4: Barratt DC, Penney G, Chan CS, Slomczykowski M, Carter TJ, Edwards PJ, Hawkes DJ.
Self-calibrating ultrasound-to-CT bone registration.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2005;8(Pt 1):605-12.

5: Barratt DC, Penney GP, Chan CS, Slomczykowski M, Carter TJ, Edwards PJ, Hawkes DJ.
Self-calibrating 3D-ultrasound-based bone registration for minimally invasive orthopedic surgery.
IEEE Trans Med Imaging. 2006 Mar;25(3):312-23.

6: Penney GP, Barratt DC, Chan CS, Slomczykowski M, Carter TJ, Edwards PJ, Hawkes DJ.
Cadaver validation of intensity-based ultrasound to CT registration.
Med Image Anal. 2006 Jun;10(3):385-95. Epub 2006 Mar 7.

7: Blackall JM, Penney GP, King AP, Hawkes DJ.
Alignment of sparse freehand 3-D ultrasound with preoperative images of the liver using models of respiratory motion and deformation.
IEEE Trans Med Imaging. 2005 Nov;24(11):1405-16.

8: Penney GP, Blackall JM, Hamady MS, Sabharwal T, Adam A, Hawkes DJ.
Registration of freehand 3D ultrasound and magnetic resonance liver images.
Med Image Anal. 2004 Mar;8(1):81-91.

X-Rays

1: Hipwell JH, Tanner C, Crum WR, Schnabel JA, Hawkes DJ.
A new validation method for X-ray mammogram registration algorithms using a
projection model of breast X-ray compression.
IEEE Trans Med Imaging. 2007 Sep;26(9):1190-200.

2: Penney GP, Edwards PJ, Hipwell JH, Slomczykowski M, Revie I, Hawkes DJ.
Postoperative calculation of acetabular cup position using 2-D-3-D registration.
IEEE Trans Biomed Eng. 2007 Jul;54(7):1342-8.

3: Sermesant M, Coudière Y, Moreau-Villèger V, Rhode KS, Hill DL, Razavi RS.
A fast-marching approach to cardiac electrophysiology simulation for XMR interventional imaging.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2005;8(Pt 2):607-15.


4: Sanchez-Ortiz GI, Sermesant M, Rhode KS, Chandrashekara R, Razavi R, Hill DL, Rueckert D.
Localization of abnormal conduction pathways for tachyarrhythmia treatment using tagged MRI.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2005;8(Pt 1):425-33.

5: Sermesant M, Rhode K, Sanchez-Ortiz GI, Camara O, Andriantsimiavona R, Hegde S, Rueckert D, Lambiase P, Bucknall C, Rosenthal E, Delingette H, Hill DL, Ayache N, Razavi R.
Simulation of cardiac pathologies using an electromechanical biventricular model and XMR interventional imaging.
Med Image Anal. 2005 Oct;9(5):467-80.

6: Rhode KS, Lambrou T, Hawkes DJ, Seifalian AM.
Novel approaches to the measurement of arterial blood flow from dynamic digital X-ray images.
IEEE Trans Med Imaging. 2005 Apr;24(4):500-13.

7: Hipwell JH, Penney GP, McLaughlin RA, Rhode K, Summers P, Cox TC, Byrne JV, Noble JA, Hawkes DJ.
Intensity-based 2-D-3-D registration of cerebral angiograms.
IEEE Trans Med Imaging. 2003 Nov;22(11):1417-26.

8: Weese J, Penney GP, Desmedt P, Buzug TM, Hill DL, Hawkes DJ.

Voxel-based 2-D/3-D registration of fluoroscopy images and CT scans for image-guided surgery.
IEEE Trans Inf Technol Biomed. 1997 Dec;1(4):284-93.

9: Hill DL, Langsaeter LA, Poynter-Smith PN, Emery CL, Summers PE, Keevil SF, Pracy JP, Walsh R, Hawkes DJ, Gleeson MJ.
Feasibility study of magnetic resonance imaging-guided intranasal flexible microendoscopy.
Comput Aided Surg. 1997;2(5):264-75.

10: Edwards PJ, Hawkes DJ, Hill DL, Jewell D, Spink R, Strong A, Gleeson M.
Augmentation of reality using an operating microscope for otolaryngology and neurosurgical guidance.
J Image Guid Surg. 1995;1(3):172-8.

11: Gandhe AJ, Hill DL, Studholme C, Hawkes DJ, Ruff CF, Cox TC, Gleeson MJ, Strong AJ.
Combined and three-dimensional rendered multimodal data for planning cranial base surgery: a prospective evaluation.
Neurosurgery. 1994 Sep;35(3):463-70; discussion 471.

12: Hawkes DJ, Seifalian AM, Colchester AC, Iqbal N, Hardingham CR, Bladin CF, Hobbs KE.
Validation of volume blood flow measurements using three-dimensional distance-concentration functions derived from digital x-ray angiograms.
Invest Radiol. 1994 Apr;29(4):434-42.

13: Brunt JN, Wicks DA, Hawkes DJ, Seifalian AM, du Boulay GH, Colchester AF, Wallis A.
The measurement of blood flow waveforms from X-ray angiography. Part 1: Principles of the method and preliminary validation.
Proc Inst Mech Eng [H]. 1992;206(2):73-85.

14: Lynch JA, Hawkes DJ, Buckland-Wright JC.
Analysis of texture in macroradiographs of osteoarthritic knees using the fractal signature.
Phys Med Biol. 1991 Jun;36(6):709-22.

15: Lynch JA, Hawkes DJ, Buckland-Wright JC.
A robust and accurate method for calculating the fractal signature of texture in macroradiographs of osteoarthritic knees.
Med Inform (Lond). 1991 Apr-Jun;16(2):241-51.

16: Hawkes DJ, Hardingham CR, Colchester AC.
Matching of geometric models in the analysis of lumen shape in digital X-ray angiography.
Prog Clin Biol Res. 1991;363:341-53. No abstract available.

17: Hawkes DJ, Robinson L, Crossman JE, Sayman HB, Mistry R, Maisey MN, Spencer JD.
Registration and display of the combined bone scan and radiograph in the
diagnosis and management of wrist injuries.
Eur J Nucl Med. 1991;18(9):752-6.

18: Seifalian AM, Hawkes DJ, Colchester AC, Hobbs KE.
A new algorithm for deriving pulsatile blood flow waveforms tested using
stimulated dynamic angiographic data.
Neuroradiology. 1989;31(3):263-9.

19: Hawkes DJ, Jackson DF, Parker RP.
Tissue analysis by dual-energy computed tomography.
Br J Radiol. 1986 Jun;59(702):537-42.

20: Hawkes DJ, Jackson DF.
An accurate parametrisation of the x-ray attenuation coefficient.
Phys Med Biol. 1980 Nov;25(6):1167-71. No abstract available.

Other

1: Yang YM, Rueckert D, Bull AM.
Predicting the shapes of bones at a joint: application to the shoulder.
Comput Methods Biomech Biomed Engin. 2007 Oct 16;:1 [Epub ahead of print]

2: Boardman JP, Counsell SJ, Rueckert D, Hajnal JV, Bhatia KK, Srinivasan L, Kapellou O, Aljabar P, Dyet LE, Rutherford MA, Allsop JM, Edwards AD.
Early growth in brain volume is preserved in the majority of preterm infants.
Ann Neurol. 2007 Aug;62(2):185-92.

3: Hawkes DJ, Mak J.
Lipid membrane; a novel target for viral and bacterial pathogens.
Curr Drug Targets. 2006 Dec;7(12):1615-21. Review.

4: Perperidis D, Mohiaddin R, Rueckert D.
Construction of a 4D statistical atlas of the cardiac anatomy and its use in classification.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2005;8(Pt 2):402-10.

5: Aljabar P, Hajnal JV, Boyes RG, Rueckert D.
Interpolation artefacts in non-rigid registration.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist
Interv. 2005;8(Pt 2):247-54.

6: Aylward SR, Cleary KR, Hawkes DJ.
Intraoperative image processing for surgical guidance.
IEEE Trans Med Imaging. 2005 Nov;24(11):1401-4. No abstract available.

7: Carter TJ, Sermesant M, Cash DM, Barratt DC, Tanner C, Hawkes DJ.
Application of soft tissue modelling to image-guided surgery.
Med Eng Phys. 2005 Dec;27(10):893-909. Epub 2005 Nov 3. Review.

8: McLaughlin RA, Hipwell J, Hawkes DJ, Noble JA, Byrne JV, Cox TC.
A comparison of a similarity-based and a feature-based 2-D-3-D registration method for neurointerventional use.
IEEE Trans Med Imaging. 2005 Aug;24(8):1058-66.

9: Hawkes DJ, Barratt D, Blackall JM, Chan C, Edwards PJ, Rhode K, Penney GP, McClelland J, Hill DL.
issue deformation and shape models in image-guided interventions: a discussion paper.
Med Image Anal. 2005 Apr;9(2):163-75. Epub 2004 Dec 28.

10: Larkman DJ, Atkinson D, Hajnal JV.
Artifact reduction using parallel imaging methods.
Top Magn Reson Imaging. 2004 Aug;15(4):267-75. Review.

11: Rao A, Chandrashekara R, Sanchez-Ortiz GI, Mohiaddin R, Aljabar P, Hajnal JV, Puri BK, Rueckert D.
Spatial transformation of motion and deformation fields using nonrigid registration.
IEEE Trans Med Imaging. 2004 Sep;23(9):1065-76.

12: de Cunha DA, Eadie LH, Barbur JL, Hawkes DJ, Seifalian AM.
The effect of image colour distortion on evaluation of donor liver suitability for transplantation.
Comput Biol Med. 2004 Oct;34(7):615-32.

13: Chandrashekara R, Rao A, Sanchez-Ortiz GI, Mohiaddin RH, Rueckert D.
Construction of a statistical model for cardiac motion analysis using nonrigid image registration.
Inf Process Med Imaging. 2003 Jul;18:599-610.

14: Byrne JV, Colominas C, Hipwell J, Cox T, Noble JA, Penney GP, Hawkes DJ.
Assessment of a technique for 2D-3D registration of cerebral intra-arterial
angiography.
Br J Radiol. 2004 Feb;77(914):123-8.

15: Crum WR, Griffin LD, Hill DL, Hawkes DJ.
Zen and the art of medical image registration: correspondence, homology, and quality.
Neuroimage. 2003 Nov;20(3):1425-37. Review.

16: Hawkes DJ, Hill DL.
Medical imaging at Guy's Hospital, King's College London.
IEEE Trans Med Imaging. 2003 Sep;22(9):1033-41. No abstract available.

17: Fabiani ME, Hawkes DJ, Frauman AG, Tikellis C, Johnston CI, Wilkinson-Berka JL.
Regulation of angiotensin II receptors in the prostate of the transgenic (mRen-2)27 rat: effect of angiotensin-converting enzyme inhibition.
Int J Biochem Cell Biol. 2003 Jun;35(6):973-83.

18: Jannin P, Fitzpatrick JM, Hawkes DJ, Pennec X, Shahidi R, Vannier MW.
Validation of medical image processing in image-guided therapy.
IEEE Trans Med Imaging. 2002 Dec;21(12):1445-9. No abstract available.

19: Atkinson D, Hill DL.
Reconstruction after rotational motion.
Magn Reson Med. 2003 Jan;49(1):183-7.

20: Hawkes DJ, Spendley DG, Alfaham M.
Hypothesis waiting for proof: unwrapping neonates for transfer.
Arch Dis Child Fetal Neonatal Ed. 2002 Nov;87(3):F232. No abstract available.

21: Bydder GM, Rutherford MA, Hajnal JV.
How to perform diffusion-weighted imaging.
Childs Nerv Syst. 2001 Apr;17(4-5):195-201.


22: Hill DL, Batchelor PG, Holden M, Hawkes DJ.
Medical image registration.
Phys Med Biol. 2001 Mar;46(3):R1-45. Review.


23: Edwards PJ, King AP, Maurer CR Jr, de Cunha DA, Hawkes DJ, Hill DL, Gaston RP, Fenlon MR, Jusczyzck A, Strong AJ, Chandler CL, Gleeson MJ.

Design and evaluation of a system for microscope-assisted guided interventions (MAGI).
IEEE Trans Med Imaging. 2000 Nov;19(11):1082-93.

24: King AP, Edwards PJ, Maurer CR Jr, de Cunha DA, Hawkes DJ, Hill DL, Gaston RP, Fenlon MR, Strong AJ, Chandler CL, Richards A, Gleeson MJ.
A system for microscope-assisted guided interventions.
Stereotact Funct Neurosurg. 1999;72(2-4):107-11.

25: Maurer CR Jr, Gaston RP, Hill DL, Gleeson MJ, Taylor MG, Fenlon MR, Edwards PJ, Hawkes DJ.
AcouStick: An optically tracked A-mode ultrasonography system for registration in image-guided neurosurgery
Stereotact Funct Neurosurg. 1999;72(2-4):143-4. No abstract available.

26: Breeuwer M, Wadley JP, de Bliek HL, Buurman J, Desmedt PA, Gieles P, Gerritsen FA, Dorward NL, Kitchen ND, Velani B, Thomas DG, Wink O, Blankensteijn JD, Eikelboom BC, Mali WP, V

"Working with our customers, we can unlock imaging's potential to accelerate and reduce the costs of product development, and hence give more patients earlier access to effective and safe treatments."

Prof Derek Hill,
CEO, IXICO

New article

Expert Opinion on Investigational Drugs - by Derek Hill, CEO

The North American Alzheimer's Disease Neuroimaging Initiative, and similar activities in Europe, Japan, and Australia, are natural history studies that are providing new insights into the use of imaging end points in clinical trials. See the article here.